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This effect occurred in a dose- and time-dependent manner and was associated with marked suppression of HIF-1α, a transcription factor upregulated in hypoxic placentae and a principal driver of sFlt-1 expression

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Dexamethasone Injection Dexamethasone Injection (1 mL Vial) † † commercial product Product Overview Dexamethasone is a potent, long-acting synthetic fluorinated glucocorticoid first described in the late 1950s and adopted for parenteral therapy soon afterward